Swedish Parkinson Research Network, SWEPAR-net
Dr. Bergquist earned his medical degree in 1997at the University of Gothenburg, Sweden and went on to earn a PhD in pharmacology in 2002 at the University of Gothenburg. He did a postdoctoral fellowship at the University of Edinburgh from 2004-2008. Worked with Profs Dutia, Ludwig and Leng studying brain stem synaptic plasticity and mechanisms of neuropeptide release and function.
Currently, Dr. Bergquist is the Neurology registrar at Sahlgrenska University Hospital in Gothenburg and holds a Junior Research Position on a personal grant from the Swedish Research Council. He is a Board member of the recently formed Swedish Parkinson Research Network, SWEPAR-net. SWEPAR-net is a subordinate to the Swedish Movement Disorder Society and aims to stimulate preclinical, clinical and translational PD related research in Sweden.
Dr. Bergquist has a translational research profile encompassing Parkinson disease animal models, behavior and in vivo neurochemistry, in vivo physiology and clinical patophysiology. His PhD thesis described the downstream permissive role of nigral somatodendritic dopamine release for motor functions, and he has since then also worked with models of brain stem synaptic plasticity and its role in posture and balance. Recent projects concern deficits in spatial memory strategies in PD patients and the role of sensory noise for motor-, and cognitive function in the dopamine depleted brain, and in Parkinson’s disease in particular.
Andersson D., Nissbrandt H. and Bergquist F. (2006). ”Partial depletion of dopamine in substantia nigra impairs motor performance without altering striatal dopamine neurotransmission” Eur J Neurosci 24:617-624.
Brederlau A., Correia A.S., Anisimov S.V., Elmi M., Paul G., Roybon L., Morizane A., Bergquist F., Riebe I., Nannmark U., Carta M., Hanse E., Takahashi J., Sasai Y., Funa K., Brundin P., Eriksson P.S .& Li J.Y. (2006). Transplantation of human embryonic stem cell-derived cells to a rat model of Parkinson’s disease: effect of in vitro differentiation on graft survival and teratoma formation. Stem Cells 24, 1433-1440.
Bergquist, F., Ruthven, A., Ludwig, M. and Dutia, M.B (2006). “Histaminergic and glycinergic modulation of GABA release in the vestibular nuclei of normal and labyrinthectomised rats”, J Physiol, 577:857-868.
Bergquist, F., Ludwig, M. and Dutia, M.B (2008). “Role of the commissural inhibitory system in vestibular compensation in the rat”, J Physiol, 586:4441-4452.
Andersson, D.R., Björnsson, E., Bergquist F. and Nissbrandt H. (2009) “Motor activity-induced dopamine release in the substantia nigra is regulated by muscarinic receptors”, Exp Neurology, 221:251-259.
Pålsson E, Söderlund G, Klamer D, Bergquist F. (2010) Noise benefit in prepulse inhibition of the acoustic startle reflex. Psychopharmacology (Berl) pre-print online publication. DOI: 10.1007/s00213-010-2074-6.